# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4186179 | F | Antiplatelet activity in rat platelet-rich plasma assessed as inhibition of arachidonic acid-induced platelet aggregation by atomic force microscopic method | Rattus norvegicus | 2 | ALA4184154 | cell-based format | Scientific Literature | |
2. | ALA4186180 | F | Anti-thrombotic activity in Sprague-Dawley rat arterial thrombosis model assessed as reduction in thrombus weight at 1 umol/kg, po pretreated for 30 mins followed by thrombosis induction measured after 15 mins | Rattus norvegicus | 2 | ALA4184154 | organism-based format | Scientific Literature | |
3. | ALA4186181 | F | Antiplatelet activity in Sprague Dawley rat arterial thrombosis model assessed as downregulation of GP2b/3a protein expression in plasma administered at 1 umol/kg, po by ELISA | Rattus norvegicus | 2 | ALA4184154 | organism-based format | Scientific Literature | |
4. | ALA4186182 | B | Inhibition of GP2b/3a in rat platelet-rich plasma assessed as reduction in arachidonic acid-induced platelet aggregation at 10'-8 to 10'-5 M after 5 mins by aggregometric analysis | Rattus norvegicus | 3 | ALA4184154 | assay format | Scientific Literature | |
5. | ALA4186183 | B | Binding affinity to GP2b/3a in rat blood assessed as conformational change by measuring soluble GP2b/3a levels after 12 hrs by UV-spectrophotometric analysis | Rattus norvegicus | 2 | ALA4184154 | assay format | Scientific Literature |