# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4181113 | F | Antifungal activity against Botrytis cinerea assessed as inhibition of spore germination at 50 ug/ml after 6 hrs by microscopic analysis relative to control | Botrytis cinerea | 36 | ALA4177654 | organism-based format | Scientific Literature | |
2. | ALA4181114 | F | Antifungal activity against Botrytis cinerea assessed as inhibition of mycelium growth at 25 ug/ml after 48 hrs relative to control | Botrytis cinerea | 26 | ALA4177654 | organism-based format | Scientific Literature | |
3. | ALA4181117 | F | Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
4. | ALA4181118 | F | Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
5. | ALA4181119 | A | Antiproliferative activity against human NCM460 cells after 72 hrs by SRB assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
6. | ALA4181120 | B | Inhibition of mTORC2 in human HeLa cells assessed as decrease in AKT phosphorylation at S473 residue at 10 uM preincubated for 1 hr followed by EGF1 stimulation by ELISA | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
7. | ALA4181121 | B | Inhibition of mTORC2 in human HeLa cells assessed as decrease in AKT phosphorylation at S473 residue preincubated for 1 hr followed by EGF1 stimulation by ELISA | Homo sapiens | 2 | ALA4177654 | cell-based format | Scientific Literature | |
8. | ALA4181122 | B | Inhibition of mTORC2 in human HeLa cells assessed as decrease in AKT phosphorylation at S473 residue preincubated for 1 hr followed by EGF1 stimulation after 30 mins by Western blot analysis | Homo sapiens | 3 | ALA4177654 | cell-based format | Scientific Literature | |
9. | ALA4181123 | B | Inhibition of mTORC2 in human HeLa cells assessed as decrease in AKT phosphorylation at S473 residue at 0.3 to 100 uM preincubated for 1 hr followed by EGF1 stimulation after 30 mins by Western blot analysis | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
10. | ALA4181124 | B | Inhibition of mTORC1 in human HeLa cells assessed as decrease in 4E-BP1 phosphorylation at T37/46 residue at 0.3 to 100 uM preincubated for 1 hr followed by EGF1 stimulation after 30 mins by Western blot analysis | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
11. | ALA4181125 | B | Inhibition of mTORC2 in human HeLa cells assessed as decrease in AKT phosphorylation at S473 residue at 10 uM preincubated for 1 hr followed by EGF1 stimulation after 30 mins by Western blot analysis | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
12. | ALA4181126 | B | Inhibition of mTORC1 in human HeLa cells assessed as decrease in 4E-BP1 phosphorylation at T37/46 residue at 10 uM preincubated for 1 hr followed by EGF1 stimulation after 30 mins by Western blot analysis | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
13. | ALA4181127 | B | Inhibition of DNA-PK in human HeLa cells assessed as decrease in SN38-induced H2AX phosphorylation at 0.01 to 1 uM after 10 hrs by Western blot analysis | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
14. | ALA4181128 | B | Inhibition of ATM in human HeLa cells assessed as decrease in SN38-induced H2AX phosphorylation at 0.01 to 1 uM after 10 hrs by Western blot analysis | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
15. | ALA4181129 | B | Inhibition of ATR in human HeLa cells assessed as decrease in SN38-induced H2AX phosphorylation at 0.01 to 1 uM after 10 hrs by Western blot analysis | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
16. | ALA4181130 | B | Inhibition of recombinant human N-terminal His6-tagged ABL T315I mutant (27 to end residues) expressed in baculovirus Sf21 insect cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
17. | ALA4181131 | B | Inhibition of recombinant human N-terminal His6-tagged ALK (1058 to end residues) expressed in baculovirus Sf21 insect cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
18. | ALA4181132 | B | Inhibition of recombinant human N-terminal His6-tagged ARG (38 to end residues) expressed in baculovirus Sf21 insect cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
19. | ALA4181133 | B | Inhibition of recombinant human N-Terminal GST-tagged and C-terminal His6-tagged ASK1 ( 649 to 946 residues) expressed in Escherichia coli cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
20. | ALA4181134 | B | Inhibition of recombinant human full length N-terminal His6-tagged Aurora-A expressed in Sf21 cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature |