| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4201103 | B | Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Mycobacterium tuberculosis H37Rv | 13 | ALA4196176 | assay format | Scientific Literature | |
| 2. | ALA4201104 | B | Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpA expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Mycobacterium tuberculosis H37Rv | 8 | ALA4196176 | assay format | Scientific Literature | |
| 3. | ALA4201105 | B | Inhibition of human PTP1B using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Homo sapiens | 10 | ALA4196176 | single protein format | Scientific Literature | |
| 4. | ALA4201106 | B | Inhibition of human VHR using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins | Homo sapiens | 8 | ALA4196176 | single protein format | Scientific Literature | |
| 5. | ALA4201111 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 10 to 120 uM after 72 hrs post infection relative to DMSO-treated control | Mycobacterium tuberculosis variant bovis BCG | 5 | ALA4196176 | cell-based format | Scientific Literature | |
| 6. | ALA4201112 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 10 to 120 uM after 24 hrs post infection | Mycobacterium tuberculosis variant bovis BCG | 5 | ALA4196176 | cell-based format | Scientific Literature | |
| 7. | ALA4201113 | B | Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 80 uM after 72 hrs post infection | Mycobacterium tuberculosis variant bovis BCG | 4 | ALA4196176 | cell-based format | Scientific Literature | |
| 8. | ALA4201114 | A | Cytotoxicity against mouse J774A.1 cells assessed as reduction in cell viability at 50 to 150 uM after 24 hrs by MTT assay | Mus musculus | 5 | ALA4196176 | cell-based format | Scientific Literature |
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