| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4194967 | B | Binding affinity to 6His-tagged and human KDM4C tandem TUDOR domain (874 to 990 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 2. | ALA4194968 | B | Binding affinity to 6His-tagged and human KDM4B tandem TUDOR domain (916 to 1030 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 3. | ALA4194970 | B | Binding affinity to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 3 | ALA4190382 | assay format | Scientific Literature | |
| 4. | ALA4194971 | B | Binding affinity to 6His-tagged and human UHRF1 tandem TUDOR domain (126 to 285 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 5. | ALA4194972 | B | Binding affinity to 6His-tagged and human 53BP1 tandem TUDOR domain (1488 to 1611 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 6. | ALA4194973 | B | Binding affinity to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) F932A mutant expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 7. | ALA4194974 | B | Binding affinity to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) W967A mutant expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 8. | ALA4194975 | B | Binding affinity to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) Y973A mutant expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 9. | ALA4194976 | B | Binding affinity to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) expressed in Escherichia coli BL21(DE3)-T1R assessed as apparent Kd for H3(1-10)K4me3 peptide at 0.5 mM by ITC method (Rvb = 5.2 +/- 0.3 uM) | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 10. | ALA4194977 | B | Binding affinity to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) expressed in Escherichia coli BL21(DE3)-T1R assessed as apparent Kd for H3(1-10)K4me3 peptide at 1 mM by ITC method (Rvb = 5.2 +/- 0.3 uM) | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 11. | ALA4194978 | B | Binding affinity to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) expressed in Escherichia coli BL21(DE3)-T1R assessed as apparent Kd for H3(1-10)K4me3 peptide at 2.5 mM by ITC method (Rvb = 5.2 +/- 0.3 uM) | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature | |
| 12. | ALA4194979 | B | Inhibition of NanoLuc-KDM4A-TUDOR domain (unknown origin) binding to Histone H3.3-HaloTag expressed in 293T cells incubated for 18 hrs by Nano-BRET based target engagement assay | Homo sapiens | 2 | ALA4190382 | cell-based format | Scientific Literature | |
| 13. | ALA4194980 | B | Inhibition of H3(1-10)K4me3 peptide binding to thrombin cleavable N-terminal 6His tagged and 13C-IVLM labeled human KDM4A tandem TUDOR domain (897 to 1011 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC method | Homo sapiens | 1 | ALA4190382 | assay format | Scientific Literature |
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