Assay

#	Aladdin ID	Assay Type	Description	Organism	Compounds	BAO Format	Source
1.	ALA4179214	B	Binding affinity to Syrian hamster PrPC	Mesocricetus auratus	6	single protein format	Scientific Literature
2.	ALA4179218	B	Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as reduction in proteinase K-resistant PrPSc level at 10 to 100 uM incubated for 5 days followed by proteinase K digestion by Western blot method relative to control	Mus musculus	6	cell-based format	Scientific Literature
3.	ALA4179219	A	Cytotoxicity against mouse ScN2a cells infected with rodent adapted RML scrapie strain assessed as reduction in cell viability at 10 to 100 uM by MTS assay	Mus musculus	6	cell-based format	Scientific Literature
4.	ALA4179220	B	Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as reduction in proteinase K-resistant PrPSc level incubated for 5 days followed by proteinase K digestion by Western blot method relative to control	Mus musculus	6	cell-based format	Scientific Literature
5.	ALA4179221	B	Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as reduction in re-emergence of drug-resistant or drug-dependent strain of PrPres measured after second passage by Western blot	Mus musculus	2	cell-based format	Scientific Literature
6.	ALA4179222	B	Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as reduction in re-emergence of drug-resistant or drug-dependent strain of PrPres measured after third passage by Western blot	Mus musculus	2	cell-based format	Scientific Literature
7.	ALA4179223	A	Cytotoxicity against mouse ScN2a cells infected with rodent adapted RML scrapie strain assessed as reduction in cell viability at 10 to 100 uM after 21.5 hrs by MTS assay	Mus musculus	2	cell-based format	Scientific Literature
8.	ALA4179224	A	Cytotoxicity against mouse ScN2a cells infected with rodent adapted RML scrapie strain assessed as reduction in cell viability at 10 to 30 uM by MTS assay	Mus musculus	2	cell-based format	Scientific Literature