| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4189875 | B | Inhibition of Mycobacterium tuberculosis IMPDH2deltaCBS mutant expressed in Escherichia coli BL21(DE3) cells using IMP as substrate by spectrophotometric method | Mycobacterium tuberculosis | 49 | cell-based format | Scientific Literature | ||
| 2. | ALA4189876 | B | Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric method | Homo sapiens | 49 | single protein format | Scientific Literature | ||
| 3. | ALA4189877 | B | Inhibition of human GMPR2 using GMP as substrate by spectrophotometric method | Homo sapiens | 49 | single protein format | Scientific Literature | ||
| 4. | ALA4189878 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 5. | ALA4189879 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 6. | ALA4189880 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 7. | ALA4189881 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in presence of guanine by broth microdilution method | Mycobacterium tuberculosis | 32 | organism-based format | Scientific Literature | ||
| 8. | ALA4189882 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using GAST/Fe medium after 2 weeks in absence of guanine by broth microdilution method | Mycobacterium tuberculosis | 8 | organism-based format | Scientific Literature | ||
| 9. | ALA4189884 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 using 7H9/ADC/Tween medium after 1 week in absence of guanine and presence of anhydrotetracycline by Alamar blue assay | Mycobacterium tuberculosis | 4 | organism-based format | Scientific Literature | ||
| 10. | ALA4189885 | F | Antitubercular activity against Mycobacterium tuberculosis SRMV2.6 harboring IMPDH2 Y487C mutant using 7H9/ADC/Tween medium after 1 week in absence of guanine by Alamar blue assay | Mycobacterium tuberculosis | 4 | organism-based format | Scientific Literature | ||
| 11. | ALA4189886 | B | Inhibition of Mycobacterium tuberculosis IMPDH2 Y487C mutant using IMP as substrate by spectrophotometric method | Mycobacterium tuberculosis | 4 | single protein format | Scientific Literature | ||
| 12. | ALA4189888 | B | Inhibition of Mycobacterium tuberculosis IMPDH2 Y487C mutant using IMP as substrate at 15 uM by spectrophotometric method relative to control | Mycobacterium tuberculosis | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4189889 | B | Selectivity ratio of Kiapp for Mycobacterium tuberculosis IMPDH2 Y487C mutant to Kiapp for Mycobacterium tuberculosis IMPDH2deltaCBS mutant | Mycobacterium tuberculosis | 4 | assay format | Scientific Literature | ||
| 14. | ALA4355040 | B | Inhibition of Francisella tularensis IMPDH expressed in Escherichia coli BL21(DE3) deletion in guaB gene using IMP as substrate preincubated for 10 mins followed by substrate addition in presence of NAD by spectrophotometer | Francisella tularensis | 4 | assay format | Scientific Literature |
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