| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4189991 | Binding | Inhibition of human ALDH1A1 using NAD+/propionaldehyde as substrate/cofactor preincubated for 15 mins followed by substrate/cofactor addition measured for 30 mins by fluorescence assay | Homo sapiens | 107 | ALA4184337 | single protein format | Scientific Literature | |
| 2. | ALA4189992 | Binding | Inhibition of ALDH1A1 in human MIAPaCa2 cells after 30 mins by aldefluor assay | Homo sapiens | 107 | ALA4184337 | cell-based format | Scientific Literature | |
| 3. | ALA4189993 | ADME | Half life in rat liver microsomes at 1 uM after 15 mins in presence of NADPH LC-MS/MS method | Rattus norvegicus | 104 | ALA4184337 | microsome format | Scientific Literature | |
| 4. | ALA4189994 | Binding | Inhibition of human ALDH1A3 using NAD+/propionaldehyde as substrate/cofactor preincubated for 15 mins followed by substrate/cofactor addition measured for 30 mins by fluorescence assay | Homo sapiens | 2 | ALA4184337 | single protein format | Scientific Literature | |
| 5. | ALA4189995 | Binding | Inhibition of human ALDH2 using NAD+/propionaldehyde as substrate/cofactor preincubated for 15 mins followed by substrate/cofactor addition measured for 30 mins by fluorescence assay | Homo sapiens | 2 | ALA4184337 | single protein format | Scientific Literature | |
| 6. | ALA4190000 | Functional | Cytotoxicity against 3D culture of human OV90 cells assessed as decrease in cell viability after 6 days by CellTiter-Glo assay | Homo sapiens | 8 | ALA4184337 | cell-based format | Scientific Literature | |
| 7. | ALA4190002 | Binding | Inhibition of ALDH1A1 in human SKOV3TR cells assessed as potentiation of 100 nM paclitaxel-mediated cytotoxicity after 4 days by CellTiter-Glo assay | Homo sapiens | 6 | ALA4184337 | cell-based format | Scientific Literature |
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