# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4188499 | Functional | Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated NO production preincubated for 2 hrs followed by LPS stimulation measured after 18 hrs by Griess assay | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
2. | ALA4188500 | ADME | Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in cell viability at 3.3 to 90 uM after 24 hrs by MTT assay | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
3. | ALA4188501 | Binding | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated IL-6 mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by qRT-PCR assay | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
4. | ALA4188502 | Binding | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated IL-1beta mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by qRT-PCR assay | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
5. | ALA4188503 | Binding | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated TNFalpha mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by qRT-PCR assay | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
6. | ALA4188504 | Binding | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated iNOS protein level at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by Western blot assay | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
7. | ALA4188505 | Binding | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated iNOS mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by qRT-PCR method | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
8. | ALA4188506 | Binding | Inhibition of NF-kB p65 phosphorylation in mouse RAW264.7 cells at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
9. | ALA4188507 | Binding | Inhibition of NF-kB p65 signaling pathway in mouse RAW264.7 cells assessed as reduction in LPS-stimulated IkBalpha phosphorylation at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
10. | ALA4188508 | Binding | Inhibition of LPS-stimulated NF-kB p65 signaling pathway in mouse RAW264.7 cells assessed as IkBalpha accumulation at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature | |
11. | ALA4188509 | Binding | Inhibition of LPS-stimulated NF-kB p65 signaling pathway in mouse RAW264.7 cells assessed as reduction in p65 nuclear translocation at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | ALA4184272 | cell-based format | Scientific Literature |