| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4188499 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated NO production preincubated for 2 hrs followed by LPS stimulation measured after 18 hrs by Griess assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4188500 | A | Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as reduction in cell viability at 3.3 to 90 uM after 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4188501 | B | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated IL-6 mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by qRT-PCR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4188502 | B | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated IL-1beta mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by qRT-PCR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4188503 | B | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated TNFalpha mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by qRT-PCR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4188504 | B | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated iNOS protein level at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 4 hrs by Western blot assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4188505 | B | Inhibition of NF-kB signaling in mouse RAW264.7 cells assessed as reduction in LPS-stimulated iNOS mRNA level preincubated for 2 hrs followed by LPS stimulation measured after 24 hrs by qRT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4188506 | B | Inhibition of NF-kB p65 phosphorylation in mouse RAW264.7 cells at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4188507 | B | Inhibition of NF-kB p65 signaling pathway in mouse RAW264.7 cells assessed as reduction in LPS-stimulated IkBalpha phosphorylation at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4188508 | B | Inhibition of LPS-stimulated NF-kB p65 signaling pathway in mouse RAW264.7 cells assessed as IkBalpha accumulation at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4188509 | B | Inhibition of LPS-stimulated NF-kB p65 signaling pathway in mouse RAW264.7 cells assessed as reduction in p65 nuclear translocation at 3.3 to 30 uM preincubated for 2 hrs followed by LPS stimulation measured after 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature |
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