# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4201538 | ADME | Antiproliferative activity against mouse L5178Y cells after 72 hrs by MTT assay | Mus musculus | 14 | ALA4196198 | cell-based format | Scientific Literature | |
2. | ALA4201539 | ADME | Antiproliferative activity against mouse L5178Y cells harboring human ABCB1 after 72 hrs by MTT assay | Mus musculus | 14 | ALA4196198 | cell-based format | Scientific Literature | |
3. | ALA4201540 | ADME | Cytotoxicity against human COLO320 cells after 24 hrs by MTT assay | Homo sapiens | 8 | ALA4196198 | cell-based format | Scientific Literature | |
4. | ALA4201541 | ADME | Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay | Homo sapiens | 8 | ALA4196198 | cell-based format | Scientific Literature | |
5. | ALA4201542 | ADME | Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by MTT assay | Mus musculus | 8 | ALA4196198 | cell-based format | Scientific Literature | |
6. | ALA4201543 | ADME | Cytotoxicity against human MRC5 cells after 24 hrs by MTT assay | Homo sapiens | 8 | ALA4196198 | cell-based format | Scientific Literature | |
7. | ALA4201544 | Binding | Modulation of human ABCB1 expressed in mouse L5178Y cells assessed as fluorescence activity ratio at 0.2 uM pretreated for 10 mins followed by rhodamine 123 addition and measured after 20 mins by flow cytometry (Rvb = 1.01 No_unit) | Homo sapiens | 1 | ALA4196198 | cell-based format | Scientific Literature | |
8. | ALA4201545 | Binding | Modulation of human ABCB1 expressed in mouse L5178Y cells assessed as fluorescence activity ratio at 2 uM pretreated for 10 mins followed by rhodamine 123 addition and measured after 20 mins by flow cytometry (Rvb = 1.01 No_unit) | Homo sapiens | 14 | ALA4196198 | cell-based format | Scientific Literature | |
9. | ALA4201546 | Binding | Modulation of human ABCB1 expressed in mouse L5178Y cells assessed as fluorescence activity ratio at 20 uM pretreated for 10 mins followed by rhodamine 123 addition and measured after 20 mins by flow cytometry (Rvb = 1.01 No_unit) | Homo sapiens | 15 | ALA4196198 | cell-based format | Scientific Literature | |
10. | ALA4201547 | Binding | Modulation of ABCB1 (unknown origin) expressed in human COLO320 cells co-expressing LRP assessed as fluorescence activity ratio at 0.2 uM pretreated for 10 mins followed by rhodamine 123 addition and measured after 20 mins by flow cytometry (Rvb = 0.79 No_unit) | Homo sapiens | 1 | ALA4196198 | cell-based format | Scientific Literature | |
11. | ALA4201548 | Binding | Modulation of ABCB1 (unknown origin) expressed in human COLO320 cells co-expressing LRP assessed as fluorescence activity ratio at 2 uM pretreated for 10 mins followed by rhodamine 123 addition and measured after 20 mins by flow cytometry (Rvb = 0.79 No_unit) | Homo sapiens | 8 | ALA4196198 | cell-based format | Scientific Literature | |
12. | ALA4201549 | Binding | Modulation of ABCB1 (unknown origin) expressed in human COLO320 cells co-expressing LRP assessed as fluorescence activity ratio at 20 uM pretreated for 10 mins followed by rhodamine 123 addition and measured after 20 mins by flow cytometry (Rvb = 0.79 No_unit) | Homo sapiens | 9 | ALA4196198 | cell-based format | Scientific Literature | |
13. | ALA4201550 | Binding | Modulation of human ABCB1 expressed in mouse L5178Y cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring combination index at ED50 measured after 48 hrs by MTT assay | Homo sapiens | 9 | ALA4196198 | cell-based format | Scientific Literature |