| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4179488 | B | Inhibition of trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells using Arg-Glu-Lys(5-Fam)-Ile-His-Pro-Phe-His-Leu-Val-IleHis-Thr-Lys(5,6 Tamra)-Arg-CONH2 as substrate measured after 2 hrs | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 2. | ALA4179489 | B | Inhibition of renin in human plasma using angiotensinogen as substrate measured for 90 mins by [125I]-angiotensin based radioimmunoassay | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 3. | ALA4179490 | A | Inhibition of human CYP3A4 expressed in Escherichia coli co-expressing CYP-reductase using diethoxyfluorescein as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 4. | ALA4179491 | B | Selectivity ratio of IC50 for human CYP3A4 expressed in Escherichia coli co-expressing CYP-reductase to IC50 for trypsin-activated recombinant human Fc-tagged renin expressed in BacMam virus infected HEK-F cells | Homo sapiens | 9 | cell-based format | Scientific Literature |
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