| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4180464 | B | Agonist activity at rat alpha1beta1deltaepsilon nAChR expressed in HEK293 cells assessed as increase in calcium flux measured for 2 mins by Fluo-4-AM dye based FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4180465 | B | Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC-3 assessed as increase in calcium flux measured for 2 mins by Fluo-4 AM dye based FLIPR assay | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA4180466 | A | Antagonist activity at human 5-HT3A receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced calcium flux preincubated for 30 mins prior to 5-HT addition by Fluo-4 AM dye based FLIPR assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 4. | ALA4180467 | B | Selectivity ratio of IC50 for human 5-HT3A receptor expressed in HEK293 cells to EC50 for rat alpha7 nAChR expressed in HEK293 cells | 14 | cell-based format | Scientific Literature | |||
| 5. | ALA4180468 | B | Agonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as increase in calcium flux measured for 2 mins by Fluo-4-AM dye based FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4180469 | B | Agonist activity at rat alpha4beta2 nAChR expressed in HEK293 cells assessed as increase in calcium flux measured for 2 mins by Fluo-4-AM dye based FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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