| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4195559 | B | Inhibition of recombinant human C-terminal FLAG-tagged JMJD1A (2 to 1321 residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4195560 | B | Inhibition of recombinant human C-terminal FLAG-tagged JMJD3 (1043 to end residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4195561 | B | Inhibition of recombinant human N-terminal GST-tagged JMJD2C (2 to 372 residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4195562 | B | Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assay | Homo sapiens | 47 | single protein format | Scientific Literature | ||
| 5. | ALA4195563 | B | Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assay | Homo sapiens | 47 | single protein format | Scientific Literature | ||
| 6. | ALA4195566 | B | Inhibition of GLP (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA4195567 | B | Inhibition of full length recombinant human N-terminal GST-tagged DNMT3A (1 to 913 residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4195568 | B | Inhibition of recombinant mouse N-terminal His/C-terminal FLAG-tagged DNMT3B (1 to 913 residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4195569 | B | Inhibition of recombinant human BRD2 bromodomain1/bromodomain2 expressed in Escherichia coli at 10 uM relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA4195570 | B | Inhibition of recombinant human CREBBP (1081 to 1197 residues) expressed in Escherichia coli at 10 uM relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA4195571 | B | Inhibition of recombinant human N-terminal His-tagged BAZ2B (1 to 913 residues) expressed in Escherichia coli at 10 uM relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 12. | ALA4195573 | F | Antiproliferative activity against human CEMO1 cells after 48 hrs by MTS assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 13. | ALA4195574 | F | Antiproliferative activity against human OCI-LY3 cells after 48 hrs by MTS assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 14. | ALA4195575 | F | Antiproliferative activity against human OCI-LY10 cells after 48 hrs by MTS assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 15. | ALA4195576 | A | Cytotoxicity against human THLE2 cells assessed as reduction in cell viability after 72 hrs by MTS assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 16. | ALA4195577 | A | Permeability of the compound at 50 uM after 18 hrs by PAMPA | 24 | assay format | Scientific Literature | |||
| 17. | ALA4195578 | A | Inhibition of CYP1A2 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 8 | microsome format | Scientific Literature | ||
| 18. | ALA4195579 | A | Inhibition of CYP2C9 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 8 | microsome format | Scientific Literature | ||
| 19. | ALA4195580 | A | Inhibition of CYP2C19 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 8 | microsome format | Scientific Literature | ||
| 20. | ALA4195581 | A | Inhibition of CYP2D6 in human liver microsomes at 10 uM after 10 mins in presence of NADPH by LC-MS/MS analysis relative to control | Homo sapiens | 8 | microsome format | Scientific Literature |
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