| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4193095 | Binding | Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 32 | ALA4190296 | cell-based format | Scientific Literature | |
| 2. | ALA4193096 | Binding | Inhibition of recombinant human MMP8 (Phe21 to Gly467 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 32 | ALA4190296 | cell-based format | Scientific Literature | |
| 3. | ALA4193097 | Binding | Inhibition of recombinant human MMP9 (Ala20 to Asp707 residues) expressed in CHO cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 32 | ALA4190296 | cell-based format | Scientific Literature | |
| 4. | ALA4193098 | Functional | Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
| 5. | ALA4193099 | Functional | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
| 6. | ALA4193100 | Functional | Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
| 7. | ALA4193101 | Functional | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
| 8. | ALA4193102 | ADME | Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay | Homo sapiens | 33 | ALA4190296 | cell-based format | Scientific Literature | |
| 9. | ALA4193103 | Functional | Antimigratory activity against human HepG2 cells assessed as reduction in wound healing at 5 to 10 uM after 48 hrs by phase contrast microscopic method | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 10. | ALA4193104 | Functional | Cell cycle arrest in human HepG2 cells assessed as accumulation at G1-phase at 5 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 52.04%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 11. | ALA4193105 | Functional | Cell cycle arrest in human HepG2 cells assessed as accumulation at G2-phase at 5 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 6.77%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 12. | ALA4193106 | Functional | Cell cycle arrest in human HepG2 cells assessed as accumulation at S-phase at 5 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 41.19%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 13. | ALA4193107 | Functional | Cell cycle arrest in human HepG2 cells assessed as accumulation at G1-phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 52.04%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 14. | ALA4193108 | Functional | Cell cycle arrest in human HepG2 cells assessed as accumulation at G2-phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 6.77%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 15. | ALA4193109 | Functional | Cell cycle arrest in human HepG2 cells assessed as accumulation at S-phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 41.19%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 16. | ALA4193110 | Functional | Induction of apoptosis in human HepG2 cells after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 17. | ALA4193111 | Functional | Induction of apoptosis in human HepG2 cells assessed as live cells at 5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 94.8%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 18. | ALA4193112 | Functional | Induction of apoptosis in human HepG2 cells assessed as early apoptotic cells at 5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.57%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 19. | ALA4193113 | Functional | Induction of apoptosis in human HepG2 cells assessed as late apoptotic cells at 5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 3.5%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature | |
| 20. | ALA4193114 | Functional | Induction of apoptosis in human HepG2 cells assessed as necrotic cells at 5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.14%) | Homo sapiens | 1 | ALA4190296 | cell-based format | Scientific Literature |
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