# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4195900 | Binding | Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measuring reduction in [3H]thymidine incorporation preincubated for 5 days followed by [3H]thymidine addition measured after 18 hrs by liquid scintillation counting method | Homo sapiens | 42 | ALA4190408 | assay format | Scientific Literature | |
2. | ALA4195901 | Binding | Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 mins by ADP-Glo assay | Homo sapiens | 41 | ALA4190408 | assay format | Scientific Literature | |
3. | ALA4195908 | Physicochemical | Lipophilicity, log D of the compound in pH 7.4 phosphate buffer after 90 mins by LC-MS analysis | 26 | ALA4190408 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4195909 | Physicochemical | Kinetic solubility of the compound in pH 7.4 solution up to 350 uM after 90 mins | 36 | ALA4190408 | small-molecule physicochemical format | Scientific Literature |