#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4198407	B	Binding affinity to Keap1 in human HaCaT cells assessed as induction of NRF2/ARE activation-mediated HO1 expression at 1 to 10 uM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
2.	ALA4198408	A	Cell cycle arrest in human HaCaT cells assessed as accumulation at G1/S phase at 10 uM after 24 hrs by propidium iodide staining based flow cytometry	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
3.	ALA4198409	A	Cytotoxicity against human HaCaT cells assessed as reduction in cell viability by measuring morphological changes at 10 uM after 24 hrs by phase contrast microscopic method	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
4.	ALA4198410	A	Induction of apoptosis in human HaCaT cells assessed as increase in cleaved caspase-3 protein expression at 10 uM after 6 to 24 hrs by Western blot analysis	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
5.	ALA4198411	A	Induction of apoptosis in human HaCaT cells assessed as increase in cleaved PARP protein expression at 10 uM after 6 to 24 hrs by Western blot analysis	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
6.	ALA4198412	B	Binding affinity to Keap1 in human HaCaT cells harboring ARE-GFP-Luc assessed as induction of ARE-dependent GFP expression by luciferase reporter gene based fluorescent microscopic assay	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
7.	ALA4198413	B	Binding affinity to Keap1 in human HaCaT cells assessed as induction of NRF2 expression by Western blot analysis	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
8.	ALA4198414	B	Binding affinity to Keap1 in human HaCaT cells assessed as activation of NRF2 by measuring nuclear translocation of NRF2 at 10 uM after 6 to 12 hrs by immunofluorescence assay	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
9.	ALA4198415	B	Binding affinity to Keap1 in NRF2+/+ MEF assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM after 24 hrs by Western blot analysis	Mus musculus	1	ALA4196072	cell-based format	Scientific Literature
10.	ALA4198416	B	Binding affinity to Keap1 in NRF2-/- MEF assessed as induction of HO1 expression at 10 uM after 24 hrs by Western blot analysis	Mus musculus	1	ALA4196072	cell-based format	Scientific Literature
11.	ALA4198417	B	Binding affinity to Keap1 in NRF2+/+ MEF assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM up to 8 hrs by RT-PCR method	Mus musculus	1	ALA4196072	cell-based format	Scientific Literature
12.	ALA4198418	B	Binding affinity to Keap1 in NRF2-/- MEF assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM up to 8 hrs by RT-PCR method	Mus musculus	1	ALA4196072	cell-based format	Scientific Literature
13.	ALA4198421	B	Binding affinity to Keap1 in human HaCaT cells assessed as induction of NRF2/ARE activation-mediated HO1 expression at 10 uM by Western blot analysis	Homo sapiens	1	ALA4196072	cell-based format	Scientific Literature
14.	ALA4198424	A	Cytotoxicity against human HaCaT cells assessed as reduction in cell viability at 10 uM after 24 hrs by MTT method	Homo sapiens	5	ALA4196072	cell-based format	Scientific Literature
15.	ALA4198425	F	Upregulation of NRF2 expression in skin lysates of mouse at 10 umole applied topically up to 24 hrs by Western blot analysis	Mus musculus	2	ALA4196072	organism-based format	Scientific Literature
16.	ALA4198426	F	Upregulation of HO-1 expression in skin lysates of mouse at 10 umole applied topically up to 24 hrs by Western blot analysis	Mus musculus	2	ALA4196072	organism-based format	Scientific Literature
17.	ALA4198427	F	Upregulation of GCLC expression in skin lysates of mouse at 10 umole applied topically up to 24 hrs by Western blot analysis	Mus musculus	2	ALA4196072	organism-based format	Scientific Literature
18.	ALA4198428	F	Anti-carcinogenic effect in hairless mouse assessed as inhibition of number of DMBA/TPA-induced papilloma formation at 10 umol administered topically 3 times per week up to 10 weeks with TPA starting from 1 week post DMBA treatment	Mus musculus	1	ALA4196072	organism-based format	Scientific Literature
19.	ALA4198429	F	Anti-carcinogenic effect in hairless mouse assessed as inhibition of incidence of DMBA/TPA-induced papilloma formation at 10 umol administered topically 3 times per week up to 10 weeks with TPA starting from 1 week post DMBA treatment	Mus musculus	1	ALA4196072	organism-based format	Scientific Literature
20.	ALA4198430	F	Anti-carcinogenic effect in hairless mouse assessed as inhibition of DMBA/TPA-induced papilloma growth at 10 umol administered topically 3 times per week up to 10 weeks with TPA starting from 1 week post DMBA treatment by hematoxylin/eosin staining based phase-contrast microscopic method	Mus musculus	1	ALA4196072	organism-based format	Scientific Literature