# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4189991 | B | Inhibition of human ALDH1A1 using NAD+/propionaldehyde as substrate/cofactor preincubated for 15 mins followed by substrate/cofactor addition measured for 30 mins by fluorescence assay | Homo sapiens | 107 | single protein format | Scientific Literature | ||
2. | ALA4189992 | B | Inhibition of ALDH1A1 in human MIAPaCa2 cells after 30 mins by aldefluor assay | Homo sapiens | 107 | cell-based format | Scientific Literature | ||
3. | ALA4189993 | A | Half life in rat liver microsomes at 1 uM after 15 mins in presence of NADPH LC-MS/MS method | Rattus norvegicus | 104 | microsome format | Scientific Literature | ||
4. | ALA4189998 | B | Stabilization of ALDH1A1 in human OV90 cells assessed as increase in melting temperature at 70 degC after 1 hr by CETSA | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
5. | ALA4190000 | F | Cytotoxicity against 3D culture of human OV90 cells assessed as decrease in cell viability after 6 days by CellTiter-Glo assay | Homo sapiens | 8 | cell-based format | Scientific Literature |