# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4194733 | Binding | Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in ERK phosphorylation | Homo sapiens | 4 | ALA4190375 | cell-based format | Scientific Literature | |
2. | ALA4194744 | Binding | Inhibition of BRAF V600E mutant (unknown origin) | Homo sapiens | 4 | ALA4190375 | single protein format | Scientific Literature | |
3. | ALA4194756 | Functional | Cytotoxicity in human WM266.4 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | ALA4190375 | cell-based format | Scientific Literature | |
4. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
5. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA5231080 | Binding | Inhibition of B-Raf V600E mutant (unknown origin) | Homo sapiens | 16 | ALA5230104 | single protein format | Scientific Literature | |
7. | ALA5231103 | Binding | Inhibition of wild type B-Raf (unknown origin) | Homo sapiens | 9 | ALA5230104 | single protein format | Scientific Literature | |
8. | ALA5231183 | Functional | Antiproliferative activity against human A-375 cells assessed as inhibition of cell viability | Homo sapiens | 2 | ALA5230104 | cell-based format | Scientific Literature | |
9. | ALA5303715 | Toxicity | Cytotoxicity activity against human HepG2 cells assessed by CellTiter-Glo luminescent cell viability assay. | Homo sapiens | 1,545 | ALA5303711 | cell-based format | EU-OPENSCREEN dataset |