# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4182827 | F | Cytotoxicity against MRP1-expressing BHK21 cells assessed as growth inhibition at 20 uM after 72 hrs by MTT assay | Mesocricetus auratus | 20 | cell-based format | Scientific Literature | ||
2. | ALA4182828 | A | Cytotoxicity against wild type BHK21 cells assessed as reduction in cell viability at 20 uM after 72 hrs by MTT assay | Mesocricetus auratus | 20 | cell-based format | Scientific Literature | ||
3. | ALA4182829 | F | Cytotoxicity against MDR1-expressing mouse NIH/3T3 cells assessed as growth inhibition at 20 uM after 72 hrs by MTT assay | Mus musculus | 24 | cell-based format | Scientific Literature | ||
4. | ALA4182830 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability at 20 uM after 72 hrs by MTT assay | Mus musculus | 24 | cell-based format | Scientific Literature | ||
5. | ALA4182831 | F | Cytotoxicity against MRP1-expressing BHK21 cells assessed as cell death after 72 hrs by MTT assay | Mesocricetus auratus | 5 | cell-based format | Scientific Literature | ||
6. | ALA4182832 | B | Inhibition of MRP1 (unknown origin) expressed in BHK21 cells assessed as GSH efflux at 20 uM incubated for 3 hrs measured every 30 secs for 2 mins by GSH reductase enzyme based assay (Rvb = 100%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
7. | ALA4182833 | F | Resistance ratio of EC50 for MRP1-expressing BHK21 cells to EC50 for wild type BHK21 cells | Mesocricetus auratus | 5 | cell-based format | Scientific Literature | ||
8. | ALA4182834 | B | Inhibition of MRP1 (unknown origin) expressed in HEK293FlpIN cells assessed as reduction in calcein-AM efflux at 20 uM incubated for 30 mins by flow cytometric analysis relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
9. | ALA4182835 | B | Inhibition of P-gp (unknown origin) expressed in mouse NIH/3T3 cells assessed as reduction in rhodamine 123 efflux at 20 uM incubated for 30 mins by flow cytometric analysis relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
10. | ALA4182836 | B | Inhibition of BCRP (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux at 20 uM incubated for 30 mins by flow cytometric analysis relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature |