# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4190757 | B | Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21(DE3)RP cells assessed as DNA ligation at 100 uM using fluorescently labelled ds nicked DNA as substrate after 30 mins by urea gel based imaging method relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature | |
2. | ALA4190758 | B | Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21(DE3)RP cells assessed as reduction in fluorescently labelled ds nicked DNA substrate ligation at 100 uM after 30 mins by urea gel based imaging method relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature | |
3. | ALA4190760 | F | Cytotoxicity against human HepG2 cells assessed as cell death at 10 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature | |
4. | ALA4190761 | F | Cytotoxicity against human A549 cells assessed as cell death at 10 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature | |
5. | ALA4190762 | F | Cytotoxicity against human HCT116 cells assessed as cell death at 10 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature | |
6. | ALA4190763 | F | Cytotoxicity against human DLD1 cells assessed as cell death at 10 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature | |
7. | ALA4190764 | F | Cytotoxicity against human MDA-MB-231 cells assessed as cell death at 10 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature | |
8. | ALA4190765 | A | Cytotoxicity against HEK293 cells assessed as cell death at 10 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 19 | ALA4190183 | cell-based format | Scientific Literature |