#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4201103	B	Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Mycobacterium tuberculosis H37Rv	13	ALA4196176	assay format	Scientific Literature
2.	ALA4201104	B	Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpA expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Mycobacterium tuberculosis H37Rv	8	ALA4196176	assay format	Scientific Literature
3.	ALA4201105	B	Inhibition of human PTP1B using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Homo sapiens	10	ALA4196176	single protein format	Scientific Literature
4.	ALA4201106	B	Inhibition of human VHR using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Homo sapiens	8	ALA4196176	single protein format	Scientific Literature
5.	ALA4201107	B	Selectivity ratio of IC50 for human PTP1B to IC50 for Mycobacterium tuberculosis H37Rv His-tagged ptpB		4	ALA4196176	assay format	Scientific Literature
6.	ALA4201108	B	Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB H94A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Mycobacterium tuberculosis H37Rv	5	ALA4196176	assay format	Scientific Literature
7.	ALA4201109	B	Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB E129A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Mycobacterium tuberculosis H37Rv	5	ALA4196176	assay format	Scientific Literature
8.	ALA4201110	B	Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB R136A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins	Mycobacterium tuberculosis H37Rv	5	ALA4196176	assay format	Scientific Literature
9.	ALA4201111	B	Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 10 to 120 uM after 72 hrs post infection relative to DMSO-treated control	Mycobacterium tuberculosis variant bovis BCG	5	ALA4196176	cell-based format	Scientific Literature
10.	ALA4201112	B	Inhibition of Mycobacterium bovis BCG Pasteur ptpB infected in mouse J774A.1 cells assessed as reduction in intracellular bacterial burden at 10 to 120 uM after 24 hrs post infection	Mycobacterium tuberculosis variant bovis BCG	5	ALA4196176	cell-based format	Scientific Literature
11.	ALA4201114	A	Cytotoxicity against mouse J774A.1 cells assessed as reduction in cell viability at 50 to 150 uM after 24 hrs by MTT assay	Mus musculus	5	ALA4196176	cell-based format	Scientific Literature
12.	ALA4201123	A	Cmax in Dunkin Hartley guinea pig at 2.5 mg/kg, ip after 0.5 hrs post dose	Cavia porcellus	2	ALA4196176	organism-based format	Scientific Literature
13.	ALA4201124	A	Half life in Dunkin Hartley guinea pig at 2.5 mg/kg, ip	Cavia porcellus	2	ALA4196176	organism-based format	Scientific Literature
14.	ALA4201125	A	AUCinfinity in Dunkin Hartley guinea pig at 2.5 mg/kg, ip	Cavia porcellus	2	ALA4196176	organism-based format	Scientific Literature
15.	ALA4201126	A	Cmax in Dunkin Hartley guinea pig at 5 mg/kg, po after 0.25 hrs post dose	Cavia porcellus	2	ALA4196176	organism-based format	Scientific Literature
16.	ALA4201127	A	Half life in Dunkin Hartley guinea pig at 5 mg/kg, po	Cavia porcellus	2	ALA4196176	organism-based format	Scientific Literature
17.	ALA4201128	A	AUCinfinity in Dunkin Hartley guinea pig at 5 mg/kg, po	Cavia porcellus	2	ALA4196176	organism-based format	Scientific Literature
18.	ALA4201129	A	Oral bioavailability in Dunkin Hartley guinea pig at 5 mg/kg	Cavia porcellus	2	ALA4196176	organism-based format	Scientific Literature
19.	ALA4824440	F	Antitubercular activity against Mycobacterium tuberculosis H37Rv assessed as bacterial growth inhibition after 7 days by broth microdilution assay	Mycobacterium tuberculosis	60	ALA4823271	organism-based format	Scientific Literature