# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4187580 | F | Growth inhibition of human SKBR3 cells incubated for 48 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
2. | ALA4187581 | F | Growth inhibition of human MDA-MB-231 cells incubated for 48 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
3. | ALA4187582 | F | Growth inhibition of human MCF7 cells incubated for 48 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
4. | ALA4187583 | F | Selectivity index, ratio of IC50 for human MDA-MB-231 cells to IC50 for human SKBR3 cells | Homo sapiens | 23 | assay format | Scientific Literature | ||
5. | ALA4187584 | F | Selectivity index, ratio of IC50 for human MCF7 cells to IC50 for human SKBR3 cells | Homo sapiens | 23 | assay format | Scientific Literature | ||
6. | ALA4187586 | B | Inhibition of HSP27 chaperone activity in human SKBR3 cells assessed as reduction in Her2 protein level at 0.1 to 1 uM incubated for 48 hrs by Western blot | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4187587 | B | Inhibition of HSP27 chaperone activity in human SKBR3 cells assessed as reduction in Her2 protein level at 0.3 to 1 uM incubated for 48 hrs by Western blot relative to 1 uM JCC76 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4187588 | B | Inhibition of alpha-crystalline (unknown origin) chaperone activity assessed as suppression of alpha-crystalline protection against DTT-induced insulin denaturation and aggregation at 10 uM incubated for 5 mins before DTT addition | Homo sapiens | 2 | assay format | Scientific Literature | ||
9. | ALA4187589 | A | Effect on DTT-induced insulin (unknown origin) denaturation and aggregation at 10 uM pre-incubated for 5 mins before DTT addition | Homo sapiens | 2 | single protein format | Scientific Literature |