# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4198152 | Functional | Induction of ROS generation in human A549/TR cells after 24 hrs by DCFH-DA dye-based flow cytometric analysis | Homo sapiens | 1 | ALA4196065 | cell-based format | Scientific Literature | |
2. | ALA4198153 | Functional | Antiproliferative activity against human A549/TR cells at 1 uM after 72 hrs by MTT assay | Homo sapiens | 5 | ALA4196065 | cell-based format | Scientific Literature | |
3. | ALA4198154 | Functional | Antiproliferative activity against human A549/TR cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4196065 | cell-based format | Scientific Literature | |
4. | ALA4198155 | Functional | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4196065 | cell-based format | Scientific Literature | |
5. | ALA4198156 | Functional | Resistant factor, ratio of IC50 for human A549/TR cells to IC50 for human A549 cells | Homo sapiens | 8 | ALA4196065 | assay format | Scientific Literature | |
6. | ALA4198157 | Functional | Potency index, ratio of taxol IC50 to compound IC50 for antiproliferative activity against human A549/TR cells | Homo sapiens | 1 | ALA4196065 | cell-based format | Scientific Literature | |
7. | ALA4198158 | ADME | Antiproliferative activity against human MRC5 cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4196065 | cell-based format | Scientific Literature | |
8. | ALA4198159 | Functional | Induction of nitric oxide production in human A549/TR cells at 50 uM after 6 hrs by Griess assay | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature | |
9. | ALA4198160 | ADME | Induction of nitric oxide production in human MRC5 cells at 50 uM after 6 hrs by Griess assay | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature | |
10. | ALA4198161 | Functional | Growth inhibition of human A549/TR cells at 1 uM after 72 hrs in presence of GSTpi inhibitor etacrynic acid by MTT assay | Homo sapiens | 1 | ALA4196065 | assay format | Scientific Literature | |
11. | ALA4198162 | Functional | Growth inhibition of human A549/TR cells at 1 uM after 72 hrs in presence of ROS scavenger NAC by MTT assay | Homo sapiens | 1 | ALA4196065 | assay format | Scientific Literature | |
12. | ALA4198163 | Functional | Growth inhibition of human A549/TR cells at 1 uM after 72 hrs in presence of NO scavenger hemoglobin by MTT assay | Homo sapiens | 1 | ALA4196065 | assay format | Scientific Literature | |
13. | ALA4198165 | Functional | Downregulation of Lon expression in human A549/TR cells after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4196065 | cell-based format | Scientific Literature | |
14. | ALA4198167 | Functional | Induction of apoptosis in human A549/TR cells after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | ALA4196065 | cell-based format | Scientific Literature | |
15. | ALA4198168 | Functional | Induction of apoptosis in human A549/TR cells assessed as viable cells at 1.2 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 95.1%) | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature | |
16. | ALA4198169 | Functional | Induction of apoptosis in human A549/TR cells assessed as early apoptotic cells at 1.2 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 3.42%) | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature | |
17. | ALA4198170 | Functional | Induction of apoptosis in human A549/TR cells assessed as late apoptotic cells at 1.2 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.24%) | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature | |
18. | ALA4198171 | Functional | Induction of apoptosis in human A549/TR cells assessed as necrotic cells at 1.2 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.22%) | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature | |
19. | ALA4198172 | Functional | Induction of apoptosis in human A549/TR cells assessed as viable cells at 2.4 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 95.1%) | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature | |
20. | ALA4198173 | Functional | Induction of apoptosis in human A549/TR cells assessed as early apoptotic cells at 2.4 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 3.42%) | Homo sapiens | 3 | ALA4196065 | cell-based format | Scientific Literature |