# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4201991 | B | Inhibition of human ALDH1A1 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
2. | ALA4201994 | B | Inhibition of human ALDH2 at 20 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA4201995 | B | Inhibition of human ALDH3A1 at 20 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA4201996 | B | Inhibition of human ALDH1A2 at 20 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA4201997 | B | Inhibition of human ALDH1A3 at 20 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA4201998 | B | Inhibition of human recombinant ALDH1A2 assessed as reduction in of NAD(P)H formation at 20 uM incubated for 2 mins by spectrophotometry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA4201999 | B | Inhibition of human recombinant ALDH1A3 assessed as reduction in of NAD(P)H formation at 20 uM incubated for 2 mins by spectrophotometry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA4202000 | B | Reversible inhibition of human recombinant ALDH1A1 assessed as reduction in of NAD(P)H formation by gel filtration assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA4202001 | B | Non-competitive inhibition of human recombinant ALDH1A1 assessed as reduction of NAD(P)H formation using varying levels of NAD+ | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA4202002 | A | Metabolic stability in CD1 mouse liver microsomes assessed as half life at 1 uM in presence of NADPH by LC-MS/MS analysis | Mus musculus | 5 | microsome format | Scientific Literature | ||
11. | ALA4202003 | P | Thermodynamic solubility of the compound by quantitative nitrogen detection assay | 10 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA4202004 | B | Inhibition of ALDH1A3 in human PEO1 cells assessed as reduction in aldefluor positive cells up to 30 uM incubated for 30 mins by aldefluor assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA4202007 | B | Inhibition of human recombinant ALDH1A1 assessed as reduction in of NAD(P)H formation incubated for 2 mins by spectrophotometry | Homo sapiens | 28 | single protein format | Scientific Literature | ||
14. | ALA4202009 | B | Inhibition of human recombinant ALDH1A2 assessed as enzyme activity by measuring NAD(P)H formation at 20 uM incubated for 2 mins by spectrophotometry | Homo sapiens | 9 | single protein format | Scientific Literature | ||
15. | ALA4202011 | B | Inhibition of human recombinant ALDH1A3 assessed as enzyme activity by measuring NAD(P)H formation at 20 uM incubated for 2 mins by spectrophotometry | Homo sapiens | 9 | single protein format | Scientific Literature | ||
16. | ALA4202012 | B | Inhibition of human recombinant ALDH2 assessed as enzyme activity by measuring NAD(P)H formation at 20 uM incubated for 2 mins by spectrophotometry | Homo sapiens | 31 | single protein format | Scientific Literature | ||
17. | ALA4603775 | B | Inhibition of ALDH1A (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
18. | ALA5150261 | B | Inhibition of human ALDH1A1 using propionaldehyde as substrate in presence of NAD+ by UV-visible spectrophometric analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
19. | ALA5150264 | B | Inhibition of human ALDH2 using propionaldehyde as substrate in presence of NAD+ by UV-visible spectrophometric analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA5150265 | B | Inhibition of human ALDH3A1 using propionaldehyde as substrate in presence of NAD+ by UV-visible spectrophometric analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |