| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4195900 | B | Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measuring reduction in [3H]thymidine incorporation preincubated for 5 days followed by [3H]thymidine addition measured after 18 hrs by liquid scintillation counting method | Homo sapiens | 42 | assay format | Scientific Literature | ||
| 2. | ALA4195901 | B | Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 mins by ADP-Glo assay | Homo sapiens | 41 | assay format | Scientific Literature | ||
| 3. | ALA4195906 | B | Inhibition of human ERG by cell based automated patch clamp method | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 4. | ALA4195907 | A | Inhibition of CYP3A4 in human liver microsomes assessed as decrease in midazolam 1-hydroxylation by LC-MS/MS analysis | Homo sapiens | 20 | microsome format | Scientific Literature | ||
| 5. | ALA4195909 | P | Kinetic solubility of the compound in pH 7.4 solution up to 350 uM after 90 mins | 36 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA4195920 | P | Thermodynamic solubility of the compound in pH 7.4 solution after 90 mins by UVLC-MS analysis | 16 | small-molecule physicochemical format | Scientific Literature |
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