| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4188154 | B | Agonist activity at human LXRalpha expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 14 | ALA4184249 | cell-based format | Scientific Literature | |
| 2. | ALA4188155 | B | Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 14 | ALA4184249 | cell-based format | Scientific Literature | |
| 3. | ALA4188157 | B | Agonist activity at human LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene assay relative to T0901317 | Homo sapiens | 11 | ALA4184249 | cell-based format | Scientific Literature | |
| 4. | ALA4188159 | B | Agonist activity at mouse LXRalpha expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 30 uM incubated for 16 hrs by luciferase reporter gene assay | Mus musculus | 6 | ALA4184249 | cell-based format | Scientific Literature | |
| 5. | ALA4188160 | B | Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene assay | Mus musculus | 4 | ALA4184249 | cell-based format | Scientific Literature | |
| 6. | ALA4188161 | B | Agonist activity at mouse LXRbeta expressed in HEK293 cells co-expressing CMX-beta-galactosidase incubated for 16 hrs by luciferase reporter gene assay relative to T0901317 | Mus musculus | 4 | ALA4184249 | cell-based format | Scientific Literature | |
| 7. | ALA4188162 | B | Agonist activity at GAL4-tagged PPARalpha (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 8. | ALA4188163 | B | Agonist activity at GAL4-tagged PPARgamma (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 9. | ALA4188164 | B | Agonist activity at GAL4-tagged RARalpha (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 10. | ALA4188165 | B | Agonist activity at GAL4-tagged RARbeta (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 11. | ALA4188166 | B | Agonist activity at GAL4-tagged RARgamma (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 12. | ALA4188167 | B | Agonist activity at GAL4-tagged RXRalpha (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 13. | ALA4188168 | B | Agonist activity at GAL4-tagged RXRbeta (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 14. | ALA4188169 | B | Agonist activity at GAL4-tagged RXRgamma (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 15. | ALA4188170 | B | Agonist activity at GAL4-tagged FXR (unknown origin) expressed in HEK293 cells co-expressing CMX-beta-galactosidase at 0.3 to 30 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature | |
| 16. | ALA4188171 | B | Agonist activity at LXRbeta ligand-binding domain (unknown origin) incubated for 1.5 hrs using fluorescein-labeled coactivator peptide by TR-FRET competitive binding assay | Homo sapiens | 1 | ALA4184249 | single protein format | Scientific Literature | |
| 17. | ALA4188172 | B | Agonist activity at LXRbeta ligand-binding domain (unknown origin) at 3 uM incubated for 1.5 hrs using fluorescein-labeled coactivator peptide by TR-FRET competitive binding assay relative to T0901317 | Homo sapiens | 1 | ALA4184249 | single protein format | Scientific Literature | |
| 18. | ALA4188173 | B | Agonist activity at LXRalpha ligand-binding domain (unknown origin) at 0.3 uM incubated for 1.5 hrs using fluorescein-labeled coactivator peptide by TR-FRET competitive binding assay relative to T0901317 | Homo sapiens | 1 | ALA4184249 | single protein format | Scientific Literature | |
| 19. | ALA4188174 | P | Aqueous solubility of the compound in EtOH: 1/15 M phosphate buffer at pH 7.4 1:1 by HPLC method | 2 | ALA4184249 | small-molecule physicochemical format | Scientific Literature | ||
| 20. | ALA4188175 | B | Agonist activity at LXRbeta in human THP1 cells assessed as increase in ABCA1 mRNA expression at 0.1 uM by real-time quantitative RT-PCR method | Homo sapiens | 1 | ALA4184249 | cell-based format | Scientific Literature |
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