# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4197281 | Functional | Cytotoxicity against human HL60 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
2. | ALA4197282 | Functional | Cytotoxicity against human K562 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
3. | ALA4197283 | Functional | Cytotoxicity against human A549 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
4. | ALA4197284 | Functional | Cytotoxicity against human NCI-H1975 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
5. | ALA4197285 | Functional | Cytotoxicity against human MGC803 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
6. | ALA4197286 | ADME | Cytotoxicity against HEK293 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
7. | ALA4197287 | Functional | Cytotoxicity against human HO8910 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
8. | ALA4197288 | Functional | Cytotoxicity against human HCT116 cells assessed as reduction in cell proliferation after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4196027 | cell-based format | Scientific Literature | |
9. | ALA4197290 | Binding | Inhibition of DNA topoisomerase-1 (unknown origin) up to 40 uM using supercoiled pBR322 DNA as substrate preincubated with enzyme followed by substrate addition measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method | Homo sapiens | 2 | ALA4196027 | single protein format | Scientific Literature | |
10. | ALA4197291 | Binding | Inhibition of DNA topoisomerase-2 (unknown origin) at 100 uM using kinetoplast DNA as substrate measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method | Homo sapiens | 2 | ALA4196027 | assay format | Scientific Literature | |
11. | ALA4197292 | Binding | Inhibition of calf thymus DNA topoisomerase-1-mediated supercoiled pBR322 DNA relaxation assessed as stabilization of enzyme-DNA complex at 100 uM preincubated with enzyme followed by substrate addition measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis method | Bos taurus | 2 | ALA4196027 | single protein format | Scientific Literature |