# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4181675 | B | Inhibition of Plasmodium falciparum FP2 at 10 uM using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 mins by spectrofluorimetric method | Plasmodium falciparum | 24 | single protein format | Scientific Literature | ||
2. | ALA4181678 | B | Inhibition of Plasmodium falciparum DHFR at 10 uM using DHF as substrate preincubated for 15 mins followed DHF addition measured after 15 mins by spectrophotometric method | Plasmodium falciparum | 24 | single protein format | Scientific Literature | ||
3. | ALA4181679 | B | Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 mins by spectrofluorimetric method | Plasmodium falciparum | 24 | single protein format | Scientific Literature | ||
4. | ALA4181680 | B | Inhibition of Plasmodium falciparum DHFR using DHF as substrate preincubated for 15 mins followed DHF addition measured after 15 mins by spectrophotometric method | Plasmodium falciparum | 24 | single protein format | Scientific Literature | ||
5. | ALA4181682 | F | Antimalarial activity against mid-ring stage of multidrug-sensitive Plasmodium falciparum 3D7 infected in human O-positive erythrocytes after 72 hrs by SYBR Green I dye-based fluorescence assay | Plasmodium falciparum | 7 | organism-based format | Scientific Literature | ||
6. | ALA4181683 | F | In vivo antimalarial activity against Plasmodium berghei ANKA infected in BALB/c mouse assessed as reduction in parasitemia at 20 mg/kg, po administered daily for 4 days by Giemsa staining-based method | Plasmodium berghei | 4 | organism-based format | Scientific Literature | ||
7. | ALA4181685 | F | Antimalarial activity against mid-ring stage of chloroquine-resistant Plasmodium falciparum Dd2 infected in human O-positive erythrocytes after 72 hrs by SYBR Green I dye-based fluorescence assay | Plasmodium falciparum | 3 | organism-based format | Scientific Literature |