# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4200880 | F | Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assay | Mus musculus | 67 | cell-based format | Scientific Literature | ||
2. | ALA4200881 | F | Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assay relative to NTX2048 | Mus musculus | 67 | cell-based format | Scientific Literature | ||
3. | ALA4200884 | F | Increase in total plasma GLP1 level in C57BL/6 mouse at 30 mg/kg, po measured after 8 hrs relative to untreated vehicle control | Mus musculus | 22 | organism-based format | Scientific Literature | ||
4. | ALA4200885 | T | Toxicity in C57BL/6 mouse assessed as induction of excessive gallbladder filling by measuring gal bladder weight at 30 mg/kg, po measured after 8 hrs relative to untreated vehicle control | Mus musculus | 22 | organism-based format | Scientific Literature | ||
5. | ALA4200886 | A | Drug concentration in bile/gall bladder of C57BL/6 mouse at 30 mg/kg, po measured after 8 hrs by HPLC and mass spectrometry | Mus musculus | 22 | organism-based format | Scientific Literature | ||
6. | ALA4200887 | A | Plasma concentration in C57BL/6 mouse at 30 mg/kg, po measured after 8 hrs by HPLC and mass spectrometry | Mus musculus | 22 | organism-based format | Scientific Literature |