# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4181947 | B | Inhibition of human CYP1A1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell membrane format | Scientific Literature | |
2. | ALA4181948 | B | Inhibition of human CYP1B1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell membrane format | Scientific Literature | |
3. | ALA4181949 | A | Inhibition of human CYP1A2 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell membrane format | Scientific Literature | |
4. | ALA4181950 | A | Inhibition of human CYP2D6 expressed in yeast microsomal membranes using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell membrane format | Scientific Literature | |
5. | ALA4181951 | A | Inhibition of human CYP2C9 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell membrane format | Scientific Literature | |
6. | ALA4181952 | A | Inhibition of human CYP2C19 expressed in yeast microsomal membranes using 3-cyano-7-ethoxycoumarin as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell membrane format | Scientific Literature | |
7. | ALA4181953 | A | Inhibition of human CYP3A4 expressed in yeast microsomal membranes using dibenzylfluorescein as substrate measured after 10 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell membrane format | Scientific Literature | |
8. | ALA4181954 | B | Selectivity ratio of IC50 for human CYP1B1 expressed in yeast microsomal membranes to IC50 for human CYP1A1 expressed in yeast microsomal membranes | Homo sapiens | 1 | ALA4177690 | cell membrane format | Scientific Literature | |
9. | ALA4181955 | B | Selectivity ratio of IC50 for human CYP1A2 expressed in yeast microsomal membranes to IC50 for human CYP1A1 expressed in yeast microsomal membranes | Homo sapiens | 1 | ALA4177690 | cell membrane format | Scientific Literature | |
10. | ALA4181956 | B | Inhibition of recombinant human CYP1A1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell-based format | Scientific Literature | |
11. | ALA4181957 | B | Inhibition of recombinant human CYP1B1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell-based format | Scientific Literature | |
12. | ALA4181958 | A | Inhibition of recombinant human CYP1A2 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell-based format | Scientific Literature | |
13. | ALA4181959 | A | Inhibition of recombinant human CYP2D6 expressed in HEK293 cells using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell-based format | Scientific Literature | |
14. | ALA4181960 | A | Inhibition of recombinant human CYP2C9 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell-based format | Scientific Literature | |
15. | ALA4181961 | A | Inhibition of recombinant human CYP2C19 expressed in HEK293 cells using 3-cyano-7-ethoxycoumarin as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell-based format | Scientific Literature | |
16. | ALA4181962 | A | Inhibition of recombinant human CYP3A4 expressed in HEK293 cells using dibenzylfluorescein as substrate pretreated for 30 mins followed by substrate addition measured for 60 mins by fluorescence assay | Homo sapiens | 14 | ALA4177690 | cell-based format | Scientific Literature | |
17. | ALA4181963 | B | Selectivity ratio of IC50 for recombinant human CYP1B1 expressed in HEK293 cells to IC50 for recombinant human CYP1A1 expressed in HEK293 cells | Homo sapiens | 4 | ALA4177690 | cell-based format | Scientific Literature | |
18. | ALA4181964 | B | Selectivity ratio of IC50 for recombinant human CYP1A2 expressed in HEK293 cells to IC50 for recombinant human CYP1A1 expressed in HEK293 cells | Homo sapiens | 4 | ALA4177690 | cell-based format | Scientific Literature | |
19. | ALA4181965 | B | Time-dependent inhibition of human CYP1A1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate | Homo sapiens | 1 | ALA4177690 | cell membrane format | Scientific Literature | |
20. | ALA4181966 | B | Time-dependent inhibition of recombinant human CYP1A1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate | Homo sapiens | 1 | ALA4177690 | cell-based format | Scientific Literature |