# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4192660 | Functional | Antagonist activity at His6-tagged NK1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of substance-P-induced IP1 accumulation at 5 x 10'-5M preincubated for 10 mins followed by substance-P addition measured after 30 mins by HTRF-FRET assay relative to control | Homo sapiens | 33 | ALA4190268 | cell-based format | Scientific Literature | |
2. | ALA4192661 | Functional | Antagonist activity at His6-tagged NK1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of substance-P-induced IP1 accumulation at 10'-5 M preincubated for 10 mins followed by substance-P addition measured after 30 mins by HTRF-FRET assay relative to control | Homo sapiens | 22 | ALA4190268 | cell-based format | Scientific Literature |