# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4179214 | B | Binding affinity to Syrian hamster PrPC | Mesocricetus auratus | 6 | single protein format | Scientific Literature | ||
2. | ALA4179218 | B | Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as reduction in proteinase K-resistant PrPSc level at 10 to 100 uM incubated for 5 days followed by proteinase K digestion by Western blot method relative to control | Mus musculus | 6 | cell-based format | Scientific Literature | ||
3. | ALA4179219 | A | Cytotoxicity against mouse ScN2a cells infected with rodent adapted RML scrapie strain assessed as reduction in cell viability at 10 to 100 uM by MTS assay | Mus musculus | 6 | cell-based format | Scientific Literature | ||
4. | ALA4179220 | B | Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as reduction in proteinase K-resistant PrPSc level incubated for 5 days followed by proteinase K digestion by Western blot method relative to control | Mus musculus | 6 | cell-based format | Scientific Literature |