# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4186338 | F | Antiproliferative activity against human LNCAP cells expressing PSA after 3 days by MTT assay | Homo sapiens | 4 | ALA4184168 | cell-based format | Scientific Literature | |
2. | ALA4186339 | F | Antiproliferative activity against human PC3 cells after 3 days by MTT assay | Homo sapiens | 3 | ALA4184168 | cell-based format | Scientific Literature | |
3. | ALA4186343 | P | Prodrug activation in conditioned media assessed as emetine level at 10 mM after 72 hrs by HPLC-MS analysis | 1 | ALA4184168 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA4186344 | P | Prodrug activation in PBS buffer assessed as emetine formation at 10 mM after 72 hrs by HPLC-MS analysis | 1 | ALA4184168 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4186345 | A | Prodrug activation assessed as emetine formation at 10 mM in presence of 10% FBS after 72 hrs by HPLC-MS analysis | 1 | ALA4184168 | assay format | Scientific Literature | ||
6. | ALA4186346 | A | Prodrug activation assessed as human PSA mediated emetine formation at 10 mM after 72 hrs by HPLC-MS analysis | Homo sapiens | 1 | ALA4184168 | single protein format | Scientific Literature | |
7. | ALA4186347 | P | Stability in PBS buffer assessed as parent compound remaining at 10 mM after 72 hrs by HPLC-MS analysis | 1 | ALA4184168 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4186348 | A | Stability in PBS buffer assessed as human PSA mediated compound metabolism by measuring parent compound remaining at 10 mM after 72 hrs by HPLC-MS analysis | Homo sapiens | 1 | ALA4184168 | single protein format | Scientific Literature | |
9. | ALA4186349 | P | Stability assessed as parent compound remaining at 10 mM in presence of 10% FBS after 72 hrs by HPLC-MS analysis | 1 | ALA4184168 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4186350 | P | Stability in conditioned media assessed as parent compound remaining at 10 mM after 72 hrs by HPLC-MS analysis | 1 | ALA4184168 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4186358 | T | Toxicity in iv dosed Balb/C mouse | Mus musculus | 15 | ALA4184168 | organism-based format | Scientific Literature | |
12. | ALA4186362 | T | Toxicity in Balb/C mouse at >50 mg/kg, iv | Mus musculus | 1 | ALA4184168 | organism-based format | Scientific Literature |