# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4221741 | F | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
2. | ALA4221742 | F | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
3. | ALA4221743 | F | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
4. | ALA4221744 | F | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
5. | ALA4221745 | A | Antiproliferative activity against human BJ cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
6. | ALA4221746 | F | Induction of apoptosis in human SW620 cells assessed as phenotypic changes after 24 to 48 hrs by microscopic analysis | Homo sapiens | 2 | ALA4219121 | cell-based format | Scientific Literature | |
7. | ALA4221747 | F | Induction of apoptosis in human HeLa cells assessed as phenotypic changes after 24 to 48 hrs by microscopic analysis | Homo sapiens | 2 | ALA4219121 | cell-based format | Scientific Literature | |
8. | ALA4221749 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at subG1 phase at 0.5 to 1 uM after 24 hrs by propidium iodide staining based flow cytometric method | Homo sapiens | 1 | ALA4219121 | cell-based format | Scientific Literature | |
9. | ALA4221751 | F | Cell cycle arrest in human SW620 cells assessed as accumulation at subG1 phase at 0.5 to 1 uM after 24 hrs by propidium iodide staining based flow cytometric method | Homo sapiens | 1 | ALA4219121 | cell-based format | Scientific Literature | |
10. | ALA4221752 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at subG1 phase at 1 uM after 48 hrs by propidium iodide staining based flow cytometric method (Rvb = 17 to 20.1 %) | Homo sapiens | 2 | ALA4219121 | cell-based format | Scientific Literature | |
11. | ALA4221754 | F | Cell cycle arrest in human HeLa cells assessed as accumulation at subG1 phase at 0.5 uM after 48 hrs by propidium iodide staining based flow cytometric method (Rvb = 17 to 20.1 %) | Homo sapiens | 1 | ALA4219121 | cell-based format | Scientific Literature | |
12. | ALA4221755 | F | Cell cycle arrest in human SW620 cells assessed as accumulation at subG1 phase at 1 uM after 48 hrs by propidium iodide staining based flow cytometric method (Rvb = 4.1 to 11.3 %) | Homo sapiens | 2 | ALA4219121 | cell-based format | Scientific Literature | |
13. | ALA4221757 | F | Cell cycle arrest in human SW620 cells assessed as accumulation at subG1 phase at 0.5 uM after 48 hrs by propidium iodide staining based flow cytometric method (Rvb = 4.1 to 11.3 %) | Homo sapiens | 1 | ALA4219121 | cell-based format | Scientific Literature | |
14. | ALA4221762 | F | Induction of apoptosis in human SW620 cells assessed as activation of caspase-2 at 0.5 uM measured after 48 hrs by colorimetric assay | Homo sapiens | 1 | ALA4219121 | cell-based format | Scientific Literature | |
15. | ALA4221764 | F | Induction of apoptosis in human SW620 cells assessed as activation of caspase-6 at 0.5 uM measured after 48 hrs by colorimetric assay | Homo sapiens | 1 | ALA4219121 | cell-based format | Scientific Literature | |
16. | ALA4221765 | B | Binding affinity to calf thymus DNA assessed as change in melting temperature at drug/DNA ratio of 0.25 by spectrophotmetric method | Bos taurus | 10 | ALA4219121 | nucleic acid format | Scientific Literature | |
17. | ALA4221766 | B | Binding affinity to calf thymus DNA assessed as change in melting temperature at drug/DNA ratio of 0.5 by spectrophotmetric method | Bos taurus | 10 | ALA4219121 | nucleic acid format | Scientific Literature | |
18. | ALA4221767 | B | Binding affinity to calf thymus DNA assessed as change in melting temperature at drug/DNA ratio of 1 by spectrophotmetric method | Bos taurus | 7 | ALA4219121 | nucleic acid format | Scientific Literature | |
19. | ALA4221768 | B | Binding affinity to calf thymus DNA at 1 to 50 uM by circular dichroism spectral analysis | Bos taurus | 3 | ALA4219121 | nucleic acid format | Scientific Literature | |
20. | ALA4221776 | B | Poison activity at human topoisomerase2 assessed as accumulation of linear DNA at 10 to 50 uM using supercoiled pUC19 as substrate pretreated with substrate for 45 mins followed by substrate addition measured by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 3 | ALA4219121 | single protein format | Scientific Literature |