| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4223564 | B | Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET peptide substrate by FRET assay | Hepatitis C virus subtype 1a | 35 | ALA4219218 | assay format | Scientific Literature | |
| 2. | ALA4223565 | F | Antiviral activity against HCV genotype 1b infected in human Huh7.5 replicon cells assessed as reduction in viral replication incubated for 4 days by luciferase reporter gene assay | Hepacivirus hominis | 35 | ALA4219218 | organism-based format | Scientific Literature | |
| 3. | ALA4223566 | P | Aqueous solubility in pH 6.5 phosphate buffer | 16 | ALA4219218 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA4223567 | B | Inhibition of N-terminal poly-His tagged recombinant HCV genotype 2b NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET peptide substrate by FRET assay | Hepatitis C virus subtype 2b | 25 | ALA4219218 | assay format | Scientific Literature | |
| 5. | ALA4223568 | B | Inhibition of N-terminal poly-His tagged recombinant HCV genotype 3a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET peptide substrate by FRET assay | Hepatitis C virus subtype 3a | 25 | ALA4219218 | assay format | Scientific Literature | |
| 6. | ALA4223569 | A | AUC in Sprague-Dawley rat plasma at 15 mg/kg administered intraduodenally as single dose measured at 4 hrs by LC/MS/MS method | Rattus norvegicus | 14 | ALA4219218 | organism-based format | Scientific Literature | |
| 7. | ALA4223570 | A | Drug level in Sprague-Dawley rat liver at 15 mg/kg administered intraduodenally as single dose measured at 4 hrs by LC/MS/MS method | Rattus norvegicus | 14 | ALA4219218 | organism-based format | Scientific Literature |
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