| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4223737 | B | Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells at 10 uM by Fluo-4 AM dye based fluorescence assay relative to control | Homo sapiens | 8 | ALA4219228 | cell-based format | Scientific Literature | |
| 2. | ALA4223738 | B | Inhibition of NMDA receptor in rat cortical embryonic neurons assessed as reduction in NMDA-induced cytosolic calcium level at 10 uM by Fluo-4 AM dye based fluorescence assay relative to control | Rattus norvegicus | 8 | ALA4219228 | assay format | Scientific Literature | |
| 3. | ALA4223739 | B | Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 7 | ALA4219228 | cell-based format | Scientific Literature | |
| 4. | ALA4223740 | B | Reversal of okadaic acid mediated PP2A PR55alpha B regulatory subunit inactivation in human SH-SY5Y cells assessed as residual activity at 0.1 uM preincubated for 24 hrs followed by cotreatment with PPA2 inhibitor okadaic acid for 18 hrs measured over 30 mins by pNPP based spectrophotometric analysis relative to control | Homo sapiens | 1 | ALA4219228 | cell-based format | Scientific Literature | |
| 5. | ALA4223741 | B | Reversal of okadaic acid mediated PP2A PR55alpha B regulatory subunit inactivation in human SH-SY5Y cells at 0.1 uM preincubated for 24 hrs followed by cotreatment with PPA2 inhibitor okadaic acid for 18 hrs measured over 30 mins by pNPP based spectrophotometric analysis | Homo sapiens | 5 | ALA4219228 | cell-based format | Scientific Literature | |
| 6. | ALA4223742 | F | Neuroprotective activity against okadaic acid-induced cell death in human SH-SY5Y cells assessed as cell viability at 0.1 uM preincubated for 24 hrs followed by cotreatment with PPA2 inhibitor okadaic acid measured after 20 hrs by MTT assay (Rvb = 50.1 +/- 0.2%) | Homo sapiens | 7 | ALA4219228 | cell-based format | Scientific Literature | |
| 7. | ALA4223743 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 3 uM incubated for 24 hrs by MTT assay | Homo sapiens | 6 | ALA4219228 | cell-based format | Scientific Literature | |
| 8. | ALA4223744 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 10 uM incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA4219228 | cell-based format | Scientific Literature |
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