# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4221741 | F | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
2. | ALA4221742 | F | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
3. | ALA4221743 | F | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
4. | ALA4221744 | F | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
5. | ALA4221745 | A | Antiproliferative activity against human BJ cells after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4219121 | cell-based format | Scientific Literature | |
6. | ALA4221765 | B | Binding affinity to calf thymus DNA assessed as change in melting temperature at drug/DNA ratio of 0.25 by spectrophotmetric method | Bos taurus | 10 | ALA4219121 | nucleic acid format | Scientific Literature | |
7. | ALA4221766 | B | Binding affinity to calf thymus DNA assessed as change in melting temperature at drug/DNA ratio of 0.5 by spectrophotmetric method | Bos taurus | 10 | ALA4219121 | nucleic acid format | Scientific Literature | |
8. | ALA4221771 | B | Inhibition of human topoisomerase1-mediated DNA relaxation assessed as DNA intercalation at 5 to 50 uM using supercoiled pUC19 as substrate pretreated with substrate for 45 mins followed by enzyme addition measured by agarose gel electrophoresis | Homo sapiens | 4 | ALA4219121 | single protein format | Scientific Literature | |
9. | ALA4221777 | A | Drug uptake in human Caki2 cells at 50 uM measured after 5 hrs by Phalloidin CruzFluorTM 488 conjugate/propidium iodide staining based fluorescence microscopic analysis | Homo sapiens | 9 | ALA4219121 | cell-based format | Scientific Literature | |
10. | ALA4221778 | A | Drug uptake in nucleus of human Caki2 cells at 50 uM measured after 5 hrs by Phalloidin CruzFluorTM 488 conjugate/propidium iodide staining based fluorescence microscopic analysis | Homo sapiens | 9 | ALA4219121 | subcellular format | Scientific Literature | |
11. | ALA4221779 | A | Drug uptake in cytoplasm of human Caki2 cells at 50 uM measured after 5 hrs by Phalloidin CruzFluorTM 488 conjugate/propidium iodide staining based fluorescence microscopic analysis | Homo sapiens | 8 | ALA4219121 | subcellular format | Scientific Literature | |
12. | ALA4221781 | F | Cytotoxicity against human Caki2 cells after 72 hrs by MTT assay | Homo sapiens | 9 | ALA4219121 | cell-based format | Scientific Literature |