# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4223544 | B | Inhibition of Plasmodium falciparum plasmepsin-1 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate addition measured every 1 min within 8 to 15 mins by FRET assay | Plasmodium falciparum | 21 | ALA4219216 | single protein format | Scientific Literature | |
2. | ALA4223545 | B | Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate addition measured every 1 min within 8 to 15 mins by FRET assay | Plasmodium falciparum | 21 | ALA4219216 | single protein format | Scientific Literature | |
3. | ALA4223546 | B | Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate addition measured every 1 min within 8 to 15 mins by FRET assay | Plasmodium falciparum | 21 | ALA4219216 | single protein format | Scientific Literature | |
4. | ALA4223547 | B | Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate addition measured every 1 min within 8 to 15 mins by FRET assay | Homo sapiens | 21 | ALA4219216 | single protein format | Scientific Literature | |
5. | ALA4223548 | P | Solubility of the compound in Tris-buffer at pH 7.4 after 16 hrs by HPLC method | 6 | ALA4219216 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4357653 | B | Inhibition of recombinant Plasmodium falciparum Plasmepsin 2 | Plasmodium falciparum | 28 | ALA4354841 | single protein format | Scientific Literature | |
7. | ALA4357657 | B | Inhibition of recombinant Plasmodium falciparum Plasmepsin 1 | Plasmodium falciparum | 11 | ALA4354841 | single protein format | Scientific Literature | |
8. | ALA4357658 | B | Inhibition of human cathepsin D | Homo sapiens | 16 | ALA4354841 | single protein format | Scientific Literature | |
9. | ALA4357661 | B | Inhibition of recombinant Plasmodium falciparum Plasmepsin 4 | Plasmodium falciparum | 15 | ALA4354841 | single protein format | Scientific Literature | |
10. | ALA5121330 | B | Inhibition of Plasmodium falciparum 3D7 plasmepsin II | Plasmodium falciparum | 4 | ALA5120754 | single protein format | Scientific Literature | |
11. | ALA5121331 | P | Thermodynamic aqueous solubility of the compound | 163 | ALA5120754 | small-molecule physicochemical format | Scientific Literature |