# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4221048 | B | Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes after 1.5 hrs by liquid scintillation counting method | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
2. | ALA4221049 | F | Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of human CRF-stimulated cAMP accumulation after 4 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA4221050 | P | Lipophilicity, log D of the compound at pH 7.4 | 15 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA4221051 | P | Solubility of the compound in JP2 buffer at pH 6.8 at 10 mmol/L | 9 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4221052 | A | Stability in human liver microsomes assessed as compound clearance after 20 mins | Homo sapiens | 15 | microsome format | Scientific Literature |