# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4222852 | F | Antifungal activity against Histoplasma capsulatum G217B ATCC 26032 at pH 7 measured over 5 days | Histoplasma capsulatum | 35 | ALA4219175 | organism-based format | Scientific Literature | |
2. | ALA4222853 | F | Antifungal activity against wild type fluconazole-sensitive Cryptococcus neoformans serotype A H99 at pH 7 measured over 4 days | Cryptococcus neoformans | 36 | ALA4219175 | organism-based format | Scientific Literature | |
3. | ALA4222854 | A | Cytotoxicity against mouse P388D1 cells assessed as reduction in cell viability after 72 hrs by resazurin-based fluorescence assay | Mus musculus | 35 | ALA4219175 | cell-based format | Scientific Literature | |
4. | ALA4222855 | T | Therapeutic index, ratio of IC50 for mouse P388D1 cells to IC50 for Histoplasma capsulatum G217B ATCC 26032 | 35 | ALA4219175 | assay format | Scientific Literature | ||
5. | ALA4222856 | T | Therapeutic index, ratio of IC50 for mouse P388D1 cells to IC50 for wild type Cryptococcus neoformans serotype A H99 | 35 | ALA4219175 | assay format | Scientific Literature | ||
6. | ALA4222861 | P | Aqueous solubility of the compound at pH 5 | 9 | ALA4219175 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4222862 | P | Aqueous solubility of the compound at pH 7 | 9 | ALA4219175 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4222863 | P | Ratio of aqueous solubility at pH 5 to aqueous solubility at pH 7 | 9 | ALA4219175 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA4222864 | F | Antifungal activity against Histoplasma capsulatum G217B ATCC 26032 at pH 5 measured over 5 days | Histoplasma capsulatum | 9 | ALA4219175 | organism-based format | Scientific Literature | |
10. | ALA4222865 | F | Antifungal activity against wild type fluconazole-sensitive Cryptococcus neoformans serotype A H99 at pH 5 measured over 4 days | Cryptococcus neoformans | 9 | ALA4219175 | organism-based format | Scientific Literature |