# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4219881 | Binding | Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay | Homo sapiens | 21 | ALA4219039 | protein complex format | Scientific Literature | |
2. | ALA4219882 | Binding | Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay | Homo sapiens | 9 | ALA4219039 | protein complex format | Scientific Literature | |
3. | ALA4219883 | Binding | Inhibition of VBC in human HeLa cells assessed as HIF-1alpha stabilization by measuring HIF-1alpha protein levels at 50 uM after 2 hrs by Western blot analysis | Homo sapiens | 21 | ALA4219039 | cell-based format | Scientific Literature | |
4. | ALA4219886 | ADME | Passive permeability of the compound in pH 7.4 PBS at 10 uM after 5 hrs by UPLC-MS/MS method based PAMPA | 10 | ALA4219039 | assay format | Scientific Literature | ||
5. | ALA4219887 | Physicochemical | Chromatographic hydrophobicity index, log D of the compound at pH 7.4 by HPLC analysis | 9 | ALA4219039 | small-molecule physicochemical format | Scientific Literature |