# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4223479 | B | Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrs | Chlorocebus aethiops | 4 | ALA4219214 | cell-based format | Scientific Literature | |
2. | ALA4223480 | B | Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrs | Chlorocebus aethiops | 4 | ALA4219214 | cell-based format | Scientific Literature | |
3. | ALA4223481 | B | Selectivity index, ratio of IC50 for African green monkey SOAT1 expressed in CHO cells to IC50 for African green monkey SOAT2 expressed in CHO cells | Chlorocebus aethiops | 4 | ALA4219214 | cell-based format | Scientific Literature | |
4. | ALA4223482 | B | Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 mins | Chlorocebus aethiops | 4 | ALA4219214 | assay format | Scientific Literature | |
5. | ALA4223483 | B | Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 mins | Chlorocebus aethiops | 4 | ALA4219214 | assay format | Scientific Literature | |
6. | ALA4223484 | B | Selectivity index, ratio of IC50 for African green monkey SOAT1 isolated from CHO cell microsomes to IC50 for African green monkey SOAT2 isolated from CHO cell microsomes | Chlorocebus aethiops | 4 | ALA4219214 | assay format | Scientific Literature | |
7. | ALA4223485 | A | Effect on phospholipid synthesis in CHO cells expressing African green monkey SOAT1 up to 21 to 23 uM | Cricetulus griseus | 3 | ALA4219214 | cell-based format | Scientific Literature | |
8. | ALA4223486 | A | Effect on phospholipid synthesis in CHO cells expressing African green monkey SOAT2 up to 21 to 23 uM | Cricetulus griseus | 3 | ALA4219214 | cell-based format | Scientific Literature | |
9. | ALA4223487 | A | Effect on cell morphology in CHO cells expressing African green monkey SOAT1 up to 21 to 23 uM | Cricetulus griseus | 3 | ALA4219214 | cell-based format | Scientific Literature | |
10. | ALA4223488 | A | Effect on cell morphology in CHO cells expressing African green monkey SOAT2 up to 21 to 23 uM | Cricetulus griseus | 3 | ALA4219214 | cell-based format | Scientific Literature |