# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4222852 | F | Antifungal activity against Histoplasma capsulatum G217B ATCC 26032 at pH 7 measured over 5 days | Histoplasma capsulatum | 35 | ALA4219175 | organism-based format | Scientific Literature | |
2. | ALA4222853 | F | Antifungal activity against wild type fluconazole-sensitive Cryptococcus neoformans serotype A H99 at pH 7 measured over 4 days | Cryptococcus neoformans | 36 | ALA4219175 | organism-based format | Scientific Literature | |
3. | ALA4222854 | A | Cytotoxicity against mouse P388D1 cells assessed as reduction in cell viability after 72 hrs by resazurin-based fluorescence assay | Mus musculus | 35 | ALA4219175 | cell-based format | Scientific Literature | |
4. | ALA4222855 | T | Therapeutic index, ratio of IC50 for mouse P388D1 cells to IC50 for Histoplasma capsulatum G217B ATCC 26032 | 35 | ALA4219175 | assay format | Scientific Literature | ||
5. | ALA4222856 | T | Therapeutic index, ratio of IC50 for mouse P388D1 cells to IC50 for wild type Cryptococcus neoformans serotype A H99 | 35 | ALA4219175 | assay format | Scientific Literature | ||
6. | ALA4222857 | F | Antifungal activity against wild-type fluconazole-sensitive Cryptococcus neoformans serotype D B3501 measured over 4 days | Cryptococcus neoformans | 7 | ALA4219175 | organism-based format | Scientific Literature | |
7. | ALA4222858 | F | Antifungal activity against fluconazole-resistant Cryptococcus neoformans serotype A TES9 harboring erg11 mutant measured over 4 days | Cryptococcus neoformans | 7 | ALA4219175 | organism-based format | Scientific Literature | |
8. | ALA4222859 | F | Antifungal activity against fluconazole-resistant Cryptococcus neoformans serotype A MRL862 harboring erg11 mutant measured over 4 days | Cryptococcus neoformans | 7 | ALA4219175 | organism-based format | Scientific Literature | |
9. | ALA4222860 | F | Antifungal activity against RFP expressing Histoplasma capsulatum infected in LacZ-expressing mouse P388D1 cells incubated for 6 days measured daily by fluorescence assay | Histoplasma capsulatum | 4 | ALA4219175 | organism-based format | Scientific Literature |