# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4223737 | B | Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells at 10 uM by Fluo-4 AM dye based fluorescence assay relative to control | Homo sapiens | 8 | ALA4219228 | cell-based format | Scientific Literature | |
2. | ALA4223738 | B | Inhibition of NMDA receptor in rat cortical embryonic neurons assessed as reduction in NMDA-induced cytosolic calcium level at 10 uM by Fluo-4 AM dye based fluorescence assay relative to control | Rattus norvegicus | 8 | ALA4219228 | assay format | Scientific Literature | |
3. | ALA4223739 | B | Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assay | Homo sapiens | 7 | ALA4219228 | cell-based format | Scientific Literature | |
4. | ALA4223741 | B | Reversal of okadaic acid mediated PP2A PR55alpha B regulatory subunit inactivation in human SH-SY5Y cells at 0.1 uM preincubated for 24 hrs followed by cotreatment with PPA2 inhibitor okadaic acid for 18 hrs measured over 30 mins by pNPP based spectrophotometric analysis | Homo sapiens | 5 | ALA4219228 | cell-based format | Scientific Literature | |
5. | ALA4223742 | F | Neuroprotective activity against okadaic acid-induced cell death in human SH-SY5Y cells assessed as cell viability at 0.1 uM preincubated for 24 hrs followed by cotreatment with PPA2 inhibitor okadaic acid measured after 20 hrs by MTT assay (Rvb = 50.1 +/- 0.2%) | Homo sapiens | 7 | ALA4219228 | cell-based format | Scientific Literature | |
6. | ALA4223743 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 3 uM incubated for 24 hrs by MTT assay | Homo sapiens | 6 | ALA4219228 | cell-based format | Scientific Literature | |
7. | ALA4223744 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 10 uM incubated for 24 hrs by MTT assay | Homo sapiens | 3 | ALA4219228 | cell-based format | Scientific Literature |