# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4222975 | Binding | Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated for 1 hr followed by substrate addition measured after 25 mins by Nu-page gel-based phosphor screen analysis | Mus musculus | 21 | ALA4219184 | single protein format | Scientific Literature | |
2. | ALA4222976 | Functional | Antiproliferative activity against human A375 cells harboring BRAF V600E mutant after 48 hrs by MTT assay | Homo sapiens | 21 | ALA4219184 | cell-based format | Scientific Literature | |
3. | ALA4222977 | Functional | Antiproliferative activity against human HT-29 cells harboring BRAF V600E mutant after 48 hrs by MTT assay | Homo sapiens | 21 | ALA4219184 | cell-based format | Scientific Literature | |
4. | ALA4222978 | Functional | Antiproliferative activity against wild type BRAF expressing human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 21 | ALA4219184 | cell-based format | Scientific Literature | |
5. | ALA4222979 | Functional | Antiproliferative activity against wild type BRAF expressing human WM1361 cells after 48 hrs by MTT assay | Homo sapiens | 21 | ALA4219184 | assay format | Scientific Literature |