# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4222108 | Binding | Inhibition of recombinant PGAM1 (unknown origin) using 3-PG as substrate preincubated for 2 mins followed by substrate addition | Homo sapiens | 38 | ALA4219134 | single protein format | Scientific Literature | |
2. | ALA4222110 | Binding | Inhibition of enolase (unknown origin) at 5 uM using 2-PG relative to control | Homo sapiens | 20 | ALA4219134 | assay format | Scientific Literature | |
3. | ALA4222111 | Binding | Inhibition of pyruvate kinase (unknown origin) at 5 uM using 2-PG relative to control | Homo sapiens | 20 | ALA4219134 | assay format | Scientific Literature | |
4. | ALA4222112 | Binding | Inhibition of LDH (unknown origin) at 5 uM using 2-PG relative to control | Homo sapiens | 20 | ALA4219134 | single protein format | Scientific Literature | |
5. | ALA4222116 | Binding | Binding affinity to PGAM1 (unknown origin) assessed as change in melting temperature by SYPRO Orange-dye based fluorescence thermal shift assay | Homo sapiens | 1 | ALA4219134 | single protein format | Scientific Literature | |
6. | ALA4222117 | Functional | Antiproliferative activity against human H1299 cells after 72 hrs by MTT assay | Homo sapiens | 19 | ALA4219134 | cell-based format | Scientific Literature | |
7. | ALA4222118 | Functional | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 20 | ALA4219134 | cell-based format | Scientific Literature | |
8. | ALA4222119 | Functional | Antiproliferative activity against human PANC1 cells after 72 hrs by MTT assay | Homo sapiens | 20 | ALA4219134 | cell-based format | Scientific Literature |