# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4224045 | Binding | Inhibition of Pneumocystis jirovecii recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPH | Pneumocystis jirovecii | 20 | ALA4219246 | cell-based format | Scientific Literature | |
2. | ALA4224046 | ADME | Inhibition of human recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPH | Homo sapiens | 20 | ALA4219246 | cell-based format | Scientific Literature | |
3. | ALA4224047 | Toxicity | Selectivity ratio of IC50 for human recombinant DHFR to IC50 for Pneumocystis jirovecii recombinant DHFR | 20 | ALA4219246 | assay format | Scientific Literature |