| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4234435 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as relative oxalate level at 10 uM after 24 hrs | Mus musculus | 43 | cell-based format | Scientific Literature | ||
| 2. | ALA4234442 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 24 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4234443 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 48 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4234444 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 72 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4234445 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 2.5 uM after 24 hrs post treatment relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4234446 | B | Inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production at 5 uM after 72 hrs post treatment | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4234447 | A | Cytotoxicity against C57BL/6 Agxt1-/- mouse hepatocytes at 80 uM after 24 to 48 hrs by Celltiter reagent based assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4234448 | B | Potency index, ratio of EC50 for CCPST to EC50 for test compound for inhibition of glycolate oxidase in C57BL/6 Agxt1-/- mouse hepatocytes using glycolate as substrate assessed as reduction in oxalate production after 24 to 72 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4234450 | B | Inhibition of horseradish peroxidase by oxalate detection based assay | Armoracia rusticana | 1 | assay format | Scientific Literature | ||
| 10. | ALA4234451 | B | Inhibition of horseradish peroxidase at 20 uM after 1 min by sulfonated-DCIP dye based assay | Armoracia rusticana | 1 | assay format | Scientific Literature | ||
| 11. | ALA4234452 | A | Half life in mouse liver microsomes at 2 uM in presence of NADPH by LC-HRMS method | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 12. | ALA4234456 | A | Drug metabolism in mouse liver microsomes assessed as metabolite formation at 2 uM in presence of NADPH after 60 mins by LC-HRMS method | Mus musculus | 1 | microsome format | Scientific Literature |
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