| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4236562 | B | Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mins followed by icilin addition by CCD-camera-based FLASH luminometric analysis | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 2. | ALA4236564 | B | Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mins followed by icilin addition by CCD-camera-based FLASH luminometric analysis | Mus musculus | 28 | cell-based format | Scientific Literature | ||
| 3. | ALA4236565 | A | Intrinsic clearance in human liver microsomes at 1 uM after 30 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 31 | microsome format | Scientific Literature | ||
| 4. | ALA4236566 | A | Intrinsic clearance in rat liver microsomes at 1 uM after 30 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 5. | ALA4236567 | A | Transactivation of PXR in human hepatocytes assessed as upregulation of CYP3A4 mRNA expression at 1 uM after 48 hrs relative to rifampicin | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA4236568 | A | Transactivation of PXR in human hepatocytes assessed as upregulation of CYP3A4 mRNA expression at 10 uM after 48 hrs relative to rifampicin | Homo sapiens | 12 | cell-based format | Scientific Literature |
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