# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4232622 | B | Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate at 2 to 20 uM preincubated for 1 hr followed by SAH-rhodamine addition measured after 5 mins by Gel-based ABPP analysis | Homo sapiens | 26 | ALA4229400 | assay format | Scientific Literature | |
2. | ALA4232624 | B | Inhibition of SAH-rhodamine binding to NNMT in human 786-O cell soluble proteomic lysate preincubated for 1 hr followed by SAH-rhodamine addition measured after 5 mins by Gel-based ABPP analysis | Homo sapiens | 11 | ALA4229400 | assay format | Scientific Literature | |
3. | ALA4232625 | B | Inhibition of NNMT in human 786-O cell lysate using d4-nicotinamide as substrate preincubated for 1 hr followed by substrate and SAM addition measured after 15 to 30 mins by LC-MS analysis | Homo sapiens | 3 | ALA4229400 | assay format | Scientific Literature | |
4. | ALA4232635 | B | Binding affinity to NNMT C165 residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis relative to control | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
5. | ALA4232636 | B | Binding affinity to HMOX2 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 3 | ALA4229400 | assay format | Scientific Literature | |
6. | ALA4232637 | B | Binding affinity to ALDH1A1 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 2 | ALA4229400 | assay format | Scientific Literature | |
7. | ALA4232645 | B | Binding affinity to NT5DC2 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
8. | ALA4232646 | B | Binding affinity to SCP2 cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
9. | ALA4232647 | B | Binding affinity to PMPCA cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature | |
10. | ALA4232648 | B | Binding affinity to ZYX cysteine residue in human 786-O cell soluble proteomic lysate at 5 uM incubated for 1 hr followed by cell lysis by IA-alkyne probe based isoTOP-ABPP analysis | Homo sapiens | 1 | ALA4229400 | assay format | Scientific Literature |