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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4235218 | Binding | Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assay relative to AITC | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
2. | ALA4235219 | Binding | Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular calcium level by fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
3. | ALA4235220 | Binding | Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular calcium level pretreated for 5 mins followed by AITC addition by fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
4. | ALA4235221 | Binding | Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay relative to ionomycin | Homo sapiens | 6 | ALA4229500 | cell-based format | Scientific Literature | |
5. | ALA4235222 | Binding | Agonist activity at human TRPV1 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay | Homo sapiens | 6 | ALA4229500 | cell-based format | Scientific Literature | |
6. | ALA4235223 | Binding | Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular calcium level pretreated for 5 mins followed by capsaicin addition by Fluo-4-AM dye based fluorescence assay | Homo sapiens | 6 | ALA4229500 | cell-based format | Scientific Literature | |
7. | ALA4235224 | Binding | Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium level pretreated for 5 mins followed by icilin addition by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
8. | ALA4235225 | Binding | Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay relative to ionomycin | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
9. | ALA4235226 | Binding | Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
10. | ALA4235227 | Binding | Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced increase in intracellular calcium level pretreated for 5 mins followed by LPC addition by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
11. | ALA4235228 | Binding | Agonist activity at rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay relative to ionomycin | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
12. | ALA4235229 | Binding | Agonist activity at rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
13. | ALA4235230 | Binding | Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreated for 5 mins followed by thymol addition by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
14. | ALA4235231 | Binding | Agonist activity at rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay relative to ionomycin | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
15. | ALA4235232 | Binding | Agonist activity at rat TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature | |
16. | ALA4235233 | Binding | Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced increase in intracellular calcium level pretreated for 5 mins followed by GSK1016790A addition by Fluo-4-AM dye based fluorescence assay | Rattus norvegicus | 6 | ALA4229500 | cell-based format | Scientific Literature |